Leishmania Major | DATOSPDF

Heterologous Expression of Trypanosoma cruzi trans-Sialidase in Leishmania major Enhances Virulence

Immune response / Gene expression / Biological Sciences / Infection and immunity / Virulence / Genetic Testing / Mice / Female / Animals / Infection / Glycoproteins / Chagas disease / Enzyme / Neuraminidase / Immune system / Trypanosoma Cruzi / Virulence factor / Cutaneous Leishmaniasis / Sialic Acid / Heterologous Expression / Leishmania Major / Trans-Sialidase / Genetic Testing / Mice / Female / Animals / Infection / Glycoproteins / Chagas disease / Enzyme / Neuraminidase / Immune system / Trypanosoma Cruzi / Virulence factor / Cutaneous Leishmaniasis / Sialic Acid / Heterologous Expression / Leishmania Major / Trans-Sialidase

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Nuphar lutea: In vitro anti-leishmanial activity against Leishmania major promastigotes and amastigotes

Complementary and Alternative Medicine / Plant Biology / Medicinal Plants / Macrophages / Phytomedicine / Mice / Animals / Drug Resistance / Male / Alkaloids / Plant extracts / Trypanocidal Agents / Nuphar / Leishmania Major / Mice / Animals / Drug Resistance / Male / Alkaloids / Plant extracts / Trypanocidal Agents / Nuphar / Leishmania Major

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Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

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Myristoyl-CoA:protein N-myristoyltransferase, an essential enzyme and potential drug target in kinetoplastid parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

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LeishCyc: a biochemical pathways database for Leishmania major

Data Mining / Metabolomics / Proteomics / Humans / System Analysis / Animals / Error Correction / Genome Annotation / Spectrum / Digestive Tract / Plasmodium falciparum / Yeast Metabolite Profiling / Genome sequence / Protozoan Proteins / Metabolic pathway / Literature Search / Drug Targeting / Leishmania Major / Web Interface / Animals / Error Correction / Genome Annotation / Spectrum / Digestive Tract / Plasmodium falciparum / Yeast Metabolite Profiling / Genome sequence / Protozoan Proteins / Metabolic pathway / Literature Search / Drug Targeting / Leishmania Major / Web Interface

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LeishCyc: a biochemical pathways database for Leishmania major

Data Mining / Metabolomics / Proteomics / Humans / System Analysis / Animals / Error Correction / Genome Annotation / Spectrum / Digestive Tract / Plasmodium falciparum / Yeast Metabolite Profiling / Genome sequence / Protozoan Proteins / Metabolic pathway / Literature Search / Drug Targeting / Leishmania Major / Web Interface / Animals / Error Correction / Genome Annotation / Spectrum / Digestive Tract / Plasmodium falciparum / Yeast Metabolite Profiling / Genome sequence / Protozoan Proteins / Metabolic pathway / Literature Search / Drug Targeting / Leishmania Major / Web Interface

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Quinuclidine Derivatives as Potential Antiparasitics

Microbiology / Medical Microbiology / Animals / Enzyme / Rats / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure

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Quinuclidine Derivatives as Potential Antiparasitics

Microbiology / Medical Microbiology / Animals / Enzyme / Rats / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure

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Increased transmission potential of Leishmania major/Leishmania infantum hybrids

Genetics / Microbiology / Zoology / Female / Animals / Emerging disease / For / Veterinary Sciences / Psychodidae / Leishmania infantum / Leishmania Major / Phlebotomus / Emerging disease / For / Veterinary Sciences / Psychodidae / Leishmania infantum / Leishmania Major / Phlebotomus

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Generation of stable L. major+EGFP/LUC and simultaneous comparison between EGFP and luciferase sensitivity

Microbiology / Experimental parasitology / Mice / Female / Animals / Genetically modified organisms / Time Factors / Cutaneous Leishmaniasis / Transfection / Veterinary Sciences / Leishmania Major / Genetically modified organisms / Time Factors / Cutaneous Leishmaniasis / Transfection / Veterinary Sciences / Leishmania Major

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Quinuclidine Derivatives as Potential Antiparasitics

Microbiology / Medical Microbiology / Animals / Enzyme / Rats / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure / Trypanosoma Cruzi / Trypanosoma brucei / Trypanosoma brucei brucei / Plasmodium falciparum / Antimicrobial agents / Sterols / Structure activity Relationship / Recombinant Proteins / Drug Targeting / Leishmania Major / Plasma Membrane / Area of Interest / Molecular Structure

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Phlebotomus papatasi and Leishmania major parasites express α-amylase and α-glucosidase

Biological Sciences / Enzyme / Growth rate / Salivary Gland / Leishmania Major

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Leishmania major CorA-like magnesium transporters play a critical role in parasite development and virulence

Microbiology / Zoology / Macrophages / Virulence / Protein Design / Magnesium / Mice / Animals / Endoplasmic Reticulum / Life Cycle / Membrane transport proteins / For / Cutaneous Leishmaniasis / Veterinary Sciences / Protozoan Proteins / Ion Transport / Virulence Factors / Structural Similarity Index / Drug Targeting / Leishmania Major / Magnesium / Mice / Animals / Endoplasmic Reticulum / Life Cycle / Membrane transport proteins / For / Cutaneous Leishmaniasis / Veterinary Sciences / Protozoan Proteins / Ion Transport / Virulence Factors / Structural Similarity Index / Drug Targeting / Leishmania Major

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Diffuse cutaneous leishmaniasis due to Leishmania major in Senegal

Microbiology / Medical Microbiology / Senegal / Humans / Female / Animals / Middle Aged / Public health systems and services research / Organometallic Compounds / Leishmania Major / Animals / Middle Aged / Public health systems and services research / Organometallic Compounds / Leishmania Major

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New tubulins in protozoal parasites

Biological Sciences / Animals / Burns / Current / Trypanosoma brucei brucei / Tubulin / Protozoan Proteins / Amino Acid Sequence / Leishmania Major / Tubulin / Protozoan Proteins / Amino Acid Sequence / Leishmania Major

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Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites

Kinetics / Drug development / Biological Chemistry / Leishmania / Cell Division / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting / Biological Sciences / Saccharomyces cerevisiae / Molecular / RNA interference / Virulence / Cell line / Humans / Mice / Endocytosis / Animals / Cell Death / Biological / Polymerase Chain Reaction / Capsid / Phenotype / Enzyme / CHEMICAL SCIENCES / Mouse Model / Rats / Trypanosoma / Trypanosoma brucei / Time Factors / Trypanosoma brucei brucei / Isoenzymes / Fatty Acid / Protozoan Proteins / Species Specificity / Amino Acid Sequence / Subcellular Fractions / Golgi Apparatus / Recombinant Proteins / Drug Targeting / Cell Survival / Leishmania Major / Biochemistry and cell biology / Poliovirus / Immunoblotting

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